Established senescence biomarkers, including increased activity of senescence‐associated‐galactosidase (SA‐β‐GAL) and cell cycle arrest proteins (p16 and p21), have been detected both in fibroblasts and alveolar epithelial cells in human IPF tissue and bleomycin (BLM)‐induced pulmonary fibrosis tissue in mice (Kunitake et al., 1998; Lomas et al., 2012; Rangarajan et al., 2022; Schafer et al., 2017). This evidence concerns the gene CDKN2A and idiopathic pulmonary fibrosis.