POF can be diagnosed in women before the age of 40 if they have diminished ovarian reserve, decreased follicular number with attenuated oocyte quality, amenorrhea or scanty menstruation, infertility and/or elevated pituitary gonadotropin concentrations (peripheral follicle‐stimulating hormone (FSH) >40 U/L).3, 4, 6. Here, BRD2 is linked to premature menopause.