In subnetwork B, Cell cycle, Viral carcinogenesis, Cellular senescence, p53 signaling pathway, and Steroid hormone biosynthesis KEGG pathways were found in module 1; Focal adhesion, Ras signaling pathway, Proteoglycans in cancer, PI3K-Akt signaling pathway, and Regulation of actin cytoskeleton in module 2; and TGF-beta signaling pathway, Hippo signaling pathway, Cytokine-cytokine receptor interaction, Signaling pathways regulating pluripotency of stem cells, and Steroid hormone biosynthesis in module 3. This evidence concerns the gene AKT1 and cancer.