FGFR2 and cholangiocarcinoma: A phase IIa dose extension studied the efficacy of ICP-192 in previously treated patients with FGFR2-altered CCA, resulting in an ORR of 52.9% (9/17), an mPFS of 6.93 months, and a discontinuation rate of 0% due to TRAEs, suggesting that ICP-192 had a favorable response rate and was well tolerated [153].