For participants with hyperglycemia, the results showed that the estimates for DKD, DR or DN did not differ by gender, IMD, WC, alcohol consumption, physical activity, hypertension, use of antihypertensive medication, cholesterol-lowering medication and diabetes medication, and levels of HbA1c, HDL-C, LDL-C, IGF, TG and TC. The gene discussed is IGF1; the disease is diabetes mellitus.