The differential expressed genes (siGLUT1/NC control) were enriched in the Cell cycle, Pathways in cancer, JAK-STAT, PI3K-AKT, TGF-beta, Hppo, Focal adhesion, etc. (Fig. 5E), which was similar to previously analyzed results based on GLUT1 correlated genes from LUAD tissues (Fig. 3E). This evidence concerns the gene ALPL and cancer.