The implication of the immune context in patient prognosis is well supported by published data, which indicate that low CD8 + T-cell infiltration could be associated with cancer stem cell maintenance and tumor recurrence in pancreatic cancer [38], while in breast cancer, several studies have demonstrated the positive effect of infiltrating CD8 + lymphocytes on patient prognosis and survival [46–50]. This evidence concerns the gene CD8A and pancreatic neoplasm.