In addition, the small-molecule STING agonist, diamidobenzimidazole (diABZI) compound, exhibited a desirable anti-SARS-CoV-2 effect against a broad array of variants, especially beta COVID-19 variant (B.1.351), by hampering the virus replication via an IFN-I independent manner under the experimental settings [78]. Here, STING1 is linked to COVID-19.