When examining gene expression of 130 known epithelial integrity genes we found no apparent trends toward altered expression in patients with controlled Crohn’s disease relative to controls (supplementary materials, Fig. S2B) including MUC1 and MUC4 (supplementary materials, Fig. S2C) which have previously been shown to remain dysregulated in controlled Crohn’s disease25. This evidence concerns the gene MUC4 and Crohn disease.