There was no significant difference in LRT galectin-3 levels between patients with ARDS (median = 146.7, interquartile range [83.4-613.1] ng/ml) vs. at-risk for ARDS (119.1 [71.3–193.1], p = 0.25), as well as no differences between patients with direct vs. indirect risk factors for lung injury. Here, LGALS3 is linked to acute respiratory distress syndrome.