CSF showed Aβ42 406.65 pg/ml (reference range > 500 ng/L), T-Tau 531.1 pg/mL (reference range < 350 pg/ml) and phosphorylated Tau181 84.2pg/mL (reference range < 61) with an ATI > 0.8, consistent with AD (Fig. 2). Here, MAPT is linked to Alzheimer disease.