Chen et al. [24] demonstrated the crucial role of LDHA in promoting cardiomyocyte proliferation and enhancing cardiac repair post-myocardial infarction, linking it to succinyl coenzyme A reduction, thioredoxin reductase 1 (Txnrd1) ubiquitination inhibition, ROS alleviation, and M2 macrophage polarization. Here, TXNRD1 is linked to myocardial infarction.