On the other hand, IL32, CCL13, CXCL9, CXCL11, and IL7 have been associated with chemoattraction of activated T cells, and CCL25 has chemotactic activity on macrophages and dendritic cells.52, 53, 54, 55 Collectively, these findings from diverse techniques, such as scRNA-seq, NanoString analysis, and secretome quantification, confirmed that the IL-17A signaling pathway is perturbed in PSC ECO. This evidence concerns the gene IL17A and endocrine-cerebro-osteodysplasia syndrome.