In this study, we show that positive expression of PD‐L1 was observed in 38.46% (5/13), and CD3‐ and CD8‐positive T lymphocytes were present in 100% (13/13) of NF2‐associated meningiomas, indicating the possibility of anti‐PD‐L1 therapy for NF2‐associated meningiomas. The gene discussed is CD8A; the disease is meningioma.