NPPB and diabetes mellitus: Univariate logistic regression analyses revealed that high GDF-15 levels (p = 0.015) and diabetes (p = 0.018) were correlated with increased cardiotoxicity risk (Table 3) and high TnT levels (p = 0.081) and high NT-proBNP levels (p = 0.075) tended to be correlated with elevated cardiotoxicity risk but were not statistically significant.