IDH1 and central nervous system cancer: They achieved an accuracy of 88.39%, a sensitivity of 76.92% and a specificity of 94.52% for a TERTp mutation in primary IDH wild-type gliomas, and an accuracy of 92.59%, a sensitivity of 83.33% and a specificity of 95.24% for a TERTp mutation in primary IDH wild-type gliomas (38).