HPV infection also causes the increased stability of Unc‐51‐like autophagy activating kinase 1 (ULK1) in HNSCC cells, probably via enhanced O‐GlcNAcylation on Ser409 and Ser410, and inhibition of the chaperon‐mediated autophagy, which consequently enhances HPV‐induced autophagy to promote the viral clearance.46 This evidence concerns the gene ULK1 and head and neck squamous cell carcinoma.