In addition, the protein expression of the EMT markers Snail, E-cadherin, and vimentin, the PMTs EHMT2, PRMT5, and SETD7/9, as well as the overall protein lysine and arginine methylation levels were compared between the parental and their 5-FU desensitized equivalent CRC cells. The gene discussed is EHMT2; the disease is colorectal carcinoma.