UGT1A1 and Gilbert syndrome: This variant is in the promoter of the UGT1A1 gene, 310 bp upstream of the (TA)n repeat UGT1A1*28 (rs3064744) at the TATA box, which is known to reduce the expression of UGT1A1 enzyme on Gilbert-Meulengracht ́s Syndrome, drifting into reduced bilirubin glucuronidation (Bosma et al., 1995; Shin et al., 2015).