Other works of this and other research groups focus on constructing mathematical models using data from mouse tumor experiments, which include xenografted neuroendocrine tumor model treated by α-emitting 212Pb-DOTAMTATE [22], thyroid cancer xenograft model treated by α-emitting 212At which naturally accumulates in thyroid [23], and transgenic murine model of metastatic breast cancer treated by α-emitters 225Ac and 213Bi, conjugated with anti-HER2/neu antibodies [24]. The gene discussed is ERBB2; the disease is thyroid cancer.