MTOR and cancer: However, pathway enrichment analysis uncovered unique pathways such as AMPK signaling activation (43 genes, FDR −2.92E-06), MTOR signaling (48 genes, FDR −4.56E-05), Rap1 signaling (61 genes, FDR −4.04E-05), pathways in cancer (125 genes, FDR- 0.000102067) only active in the female liver of the BPA lineage that has been associated to cancer121–124.