In contrast, levels of histone H2A type 3 (H2AW), IGHV3-20, Fc gamma-binding protein (FCGBP), DEAH-box helicase 37, dpy-19-like 4 (DPY19L4), and zinc finger SWIM-type containing 9 (ZSWIM9) were lower in patients with AVN than in controls (Table 2). The gene discussed is H2AC25; the disease is avascular necrosis.