Our analysis revealed elevated TRAF1 expression in several cancers, notably CHOL, colon adenocarcinoma (COAD), head and neck squamous cell carcinoma (HNSC), kidney renal clear cell carcinoma (KIRC), kidney renal papillary cell carcinoma (KIRP), liver hepatocellular carcinoma (LIHC), lung adenocarcinoma (LUAD), and stomach adenocarcinoma (STAD). Here, TRAF1 is linked to colon adenocarcinoma.