Moreover, we determined the expression of RGS19 in serial clinical HCC tissue sections via IHC, and the expression of RGS19 was positively associated with the expression of MYH9 (r = 0.523, p < 0.001), β-catenin (r = 0.432, p < 0.001) and c-Myc (r = 0.437, p < 0.001) (Fig. 7b, c). The gene discussed is MYC; the disease is hepatocellular carcinoma.