Tests of HIV-1 and HIV-2 antibody, Hepatitis B antigen and antibody (IgG, IgM), Hepatitis C antibody, and serology for syphilis, except of one guideline that recommends it only in sperm donors [46] is recommended for all potential gamete/embryo donors [30, 34, 46–48]. This evidence concerns the gene CD40LG and hepatitis C virus infection.