The expression of HAVCR2, PVR, TNFRSF25, and TNFSF15 showed a positive correlation with the expression of numerous MRM-related genes like GTPBP3, METTL2A, METTL6, METTL8, NSUN4, and TRMT61A in glioma cells. The gene discussed is METTL8; the disease is central nervous system cancer.