IDH2 and neoplasm: The MRM score (AUC = 0.878) showed excellent predictive performance compared with that of IDH (AUC = 0.829), 1p19q (ACU = 0.619), radiation (AUC = 0.494), chemotherapy (AUC = 0.536), tumor grade (AUC = 0.687), and age (AUC = 0.810) (Fig. 6B).