Case 2 featured marked macrocytic anemia (RBC = 1.60 × 106/mm3, MCV = 312.50 fL, Hb = 8.8 g/dL), and leukocytosis (21,945/μl) with neutrophilia (14,923/μl) and lymphocytosis (5,486/μl), and hypoglycemia (75 mg/dL) (Ruoppolo and Loureiro 2014). The gene discussed is GSTM1; the disease is macrocytic anemia.