Our research investigated MFAP2 expression is positively correlated to macrophages in TNBC and previous study has reported the overexpression of MFAP2 is positively related to markers of Th2 cells and M2 macrophages in glioma [34], implying MFAP2 performs a crucial role in tumor immunity modulation. The gene discussed is MFAP2; the disease is central nervous system cancer.