NFE2L2 and colitis: Several experimental models have been used to study Nrf2’s capacity to maintain the intestinal barrier, including Salmonella typhi infections (Theiss et al. 2009), colitis caused by dextran sodium sulfate (Theiss et al. 2009; Li et al. 2018), intestinal ischemic-reperfusion (Chi et al. 2015; Han et al. 2016b), intestinal mucosa damage, malfunction of the epithelial barrier brought on by traumatic brain injury (Liu et al. 2017b), and intestinal burn (Chen et al. 2016).