isolated from the mammalian GIT chyme and fecal contents had functions in synthesizing enzymes to deconstruct and utilize mucin in the GIT (Gong et al. 2020; Tailford et al. 2015) and showed an anti-obesity protective effect via modulation of glucose metabolism (Zhou et al. 2020). This evidence concerns the gene MUC5AC and obesity due to melanocortin 4 receptor deficiency.