Synucleinopathies are age-related neurodegenerative diseases, including Parkinson’s disease (PD), Dementia with Lewy bodies (DLB), and Multiple System Atrophy (MSA), where the prominent neuropathological hallmark is aggregates of misfolded alpha-synuclein (αsyn) protein [1]. The gene discussed is SNCA; the disease is Lewy body dementia.