Denise et al. [29] found, in their retrospective study of COVID-19, that NSE and other biomarkers such as LDH, aspartate aminotransferase (AST), troponin, creatine kinase (CK-MB), D-dimer, and brain natriuretic peptide (BNP) can easily be used to predict the severity of disease, hospitalisation, admission to the intensive care unit (ICU), and mortality. Here, NPPB is linked to COVID-19.