In interference expression group, SVA infection increased the expression of p-NF-κB p65 (P < 0.01) and p-IκBα (P < 0.05), compared to shNC; impeded ZBP1 expression decreased the expression of p-NF-κB p65 (P < 0.05) and p-IκBα (P < 0.05), and increased the expression of IκBα (P < 0.05), compared to shNC + SVA, no significant difference in the protein levels of NF-κB at 24 h.p.i (Fig. 4C, D). Here, ZBP1 is linked to infection.