Consistently, the western blot assay revealed that protein expression of OGG1 was significantly increased in BLM group, while the protein expression of PINK1 and Parkin was significantly decreased (Fig. 1E), suggesting that OGG1/PINK1 mitophagy might be involved in the progression of pulmonary fibrosis. The gene discussed is PRKN; the disease is pulmonary fibrosis.