Scrutiny of mRNA expression from The Cancer Atlas Genome (TCGA) and ONCOMINE datasets confirmed significant elevation of Trx1 and TrxR1 in NSCLC subsets lung adenocarcinoma (LUAD) and lung squamous cell carcinoma (LUSC) (Fig. 1c and Supplementary Fig. S1a, b). Here, TXN is linked to squamous cell lung carcinoma.