Scrutiny of mRNA expression from The Cancer Atlas Genome (TCGA) and ONCOMINE datasets confirmed significant elevation of Trx1 and TrxR1 in NSCLC subsets lung adenocarcinoma (LUAD) and lung squamous cell carcinoma (LUSC) (Fig. 1c and Supplementary Fig. S1a, b). The gene discussed is KMT2A; the disease is lung adenocarcinoma.