Both groups exhibited a significant enrichment in multipotent progenitor-like phenotype (MPP-L, odds ratio 4.83, p = 0.008 and 5.42, p = 0.0005, respectively) compared with a series of 2230 patients with BCR::ABL1 negative AML (Fig. 2A and Supplementary Fig. 1). Here, BCR is linked to acute myeloid leukemia.