It is worth noting that in the xenograft mice experiments, we detected the serum IFN-γ and TNF-α after being treated with BLM alone and BLM combined with Conodin A. IFN-γ and TNF-α are crucial immunoregulatory factors that can be utilized in cancer treatment or directly inhibit tumor cell proliferation [48, 49]. The gene discussed is TNF; the disease is cancer.