Among them, THY1 expression was negatively correlated with tumor purity (cor = −0.38, P = 7.59E-28), and THY1 expression had a positive correlation with B cell (cor = 0.197, P = 1.70E-05), CD8+ cell (cor = 0.166, P = 2.70E-04), CD4+ cell (cor = 0.393, P = 5.11E-19), Macrophage (cor = 0.316, P = 1.49E-12), Neutrophil (cor = 0.412, P = 6.62E-21), and Dendritic cell (cor = 0.451, P = 4.22E-15) in LUSC. This evidence concerns the gene CD4 and neoplasm.