Correlations between organokines [meteorin-like (METRNL), fibroblast growth factor 21 (FGF21) and diazepam-binding inhibitor (DBI)] and study variables in girls with polycystic ovary syndrome (PCOS) after 6 months on an oral contraceptive (OC) or on a low-dose combination of spironolactone plus pioglitazone plus metformin (spiomet). This evidence concerns the gene FGF21 and polycystic ovary syndrome.