VANGL2 and type 1 diabetes mellitus: Indeed T1D induced a significant reduction in the protein levels of N-cadherin (N-CAD; p < 0.01; Figures 5A, B), occludin (OCN; p < 0.01; Figures 5A, C), zonula occludens-1 (ZO-1; p < 0.05; Figures 5A, D), connexin 43 (CX43; p < 0.01; Figures 5A, E), and Van Gogh-Like 2 (VANGL2; p < 0.01; Figures 5A, F) as well as in the phosphorylation status of p-Src (p < 0.01; Figures 5A, G), p-FAK-Y397 (p < 0.01; Figures 5A, H), and p-FAK-Y407 (p < 0.05; Figures 5A, I) compared to the control.