Among these genes, Transgelin 2 (TAGLN2), Filamin A (FLNA), Kinesin Family Member 23 (KIF23), Familial hypercholesterolemia (FH), H2B clustered histone 12 like (H2BS1, also known as H2BC12L), and Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma (IKBKG) were identified as high-risk genes, while Chromogenic in situ hybridization (CISH) and Cathepsin W (CTSW) were labeled as low-risk genes. This evidence concerns the gene H2BC12L and familial hyperaldosteronism.