The positive anti-LC1 rates in the AIH group were higher than those in other four groups, but this was not statistically significant after multiple testing correction (p = 0.029, 0.07, 0.052, and 0.037, respectively); the positive rate for Ro52 was significantly higher than that in the gene deficiency group, infectious liver disease group and the other etiology group (p < 0.0125). This evidence concerns the gene TRIM21 and autoimmune hepatitis.