Particularly, the pentameric -FFMMI- 224-228 aa of human GNS is contained in the transmembrane protein of Streptococcus gordonii (aa 43–47), transcriptional regulator of Lactobacillus casei (aa 464-468), acetyl-CoA carboxylase, carboxyl transferase subunit beta of Clostridium cellulolyticum H10 (aa 133-137), hypothetical protein of Vibrio phage KVP40 (aa 23-27) and several other foreign proteins, suggesting that many other triggering factors may really exacerbate GNS-specific autoreactivity in RA by molecular mimicry. This evidence concerns the gene GNS and rheumatoid arthritis.