FSCN1 and cancer: Amongthem, actin myopathies can affect the normal function of skeletalmuscles and the heart,5,6 and abnormalities of the actincytoskeleton are also associated with cancer development and metastasis.For example, it is well established that overexpression of fascin,an actin-bundling protein, has a crucial role in breast cancer developmentand can give rise to cancer cell migration, invasion, and metastaticcolonization.7,8