GJB1 and Familial prostate cancer: The data from the GEPIA database and the TCGA and GTEx programs were analyzed for 141 genes under the criteria of p < 0.01 and | log2FC| Cutoff > 1.5 criteria; the analysis of the 141 genes suggested that the expression of DTNA, GJB1 and TRPC4 were significantly different in prostate cancer patients and controls, with decreased expression of DTNA and TRPC4 (Figures 5B, D), and the opposite for GJB1 (Figure 5C).