The 20 most significant pathways containing the 10 breast cancer associated genes (TP53, epidermal growth factor receptor (EGFR), BRCA2, caspase 8 (CASP8), erb-b4 receptor tyrosine kinas 4 (ERBB4), FOXP1, breast cancer gene 1 (BRCA1), cyclin dependent kinase inhibitor 2a (CDKN2A), AKT1, CHEK2) were visualised in Fig. 7. This evidence concerns the gene CASP8 and breast cancer.