BRCA2 and ovarian cancer: A clinical study of ovarian cancer patients at Fujian Medical University Cancer Hospital revealed that 17.1% of patients carried BRCA1 pathogenic mutations and 5.3% carried BRCA2 pathogenic mutations (13); additionally, three Chinese-specific high-frequency BRCA1 mutations, c.5470_5477delATTGGGCA, c.981_982delAT, c.3770 _3771delAG, were reported.