The top 10 genes with most deleterious mutations in the Chinese ovarian cancer population were MC1R (12%), MLH1 (9%), PRKDC (8%), KIF1B (8%), FANCM (7%), FANCI (6%), PRSS1 (6%), SDHA (6%), BRCA2 (6%), and CFTR (5%) (Supplementary Figure S3). This evidence concerns the gene PRSS1 and ovarian cancer.