Comparative analysis of the difference in ovarian cancer mutation genes between the BRCA1/2 mutation group and the non-mutation group uncovered that FAM175A, EMSY, PTCH1, and HNF1B were significantly highly mutated in the group without BRCA1/2 mutations (Supplementary Figure S7A), particularly PTCH1: c.3907C>T (p.R1303C) (Supplementary Figure S7B). This evidence concerns the gene BRCA1 and ovarian cancer.