Univariate and multivariate logistic regression analyses were performed on these patients, identifying several predictive risk factors for treatment failure: advanced age, tumor location in the splenic flexure, a high TNM stage, absence of chemotherapy, positive or elevated preoperative carcinoembryonic antigen (CEA) levels, obtaining fewer than 12 lymph nodes, presence of neural invasion, and unmarried status. This evidence concerns the gene CEACAM5 and neoplasm.