IRF3 and inflammatory bowel disease: Supplementary Figures S3-8 display the classification and enrichment results for DEGs correlated with MAVS, C6orf150, TMEM173, IKBKE, TBK1, and IRF3. GSEA further indicated that MAVS, C6orf150, TMEM173, IKBKE, TBK1, and IRF3 genes were correlated with the RIG-I-like receptor signaling pathway, cytosolic DNA-sensing pathway, Hedgehog signaling pathway, IL-17 signaling pathway, inflammatory bowel disease, and Toll-like receptor signaling pathway.