By utilizing the GEPIA2 database in tandem with the TIMER2 database, we further evaluated the expression of DDX58, MAVS, C6orf150, TMEM173, IKBKE, TBK1 and IRF3 in BRCA, CHOL, colon adenocarcinoma (COAD), esophageal carcinoma (ESCA), liver hepatocellular carcinoma (LIHC), lung squamous cell carcinoma (LUSC) and stomach adenocarcinoma (STAD) in normal and tumor tissues. This evidence concerns the gene IRF3 and neoplasm.