To explore the heightened sensitivity of ovarian cancer cells to platinum-based treatment upon TACSTD2 knockout, we performed PCA dimensionality reduction and WGCNA analysis on sequencing data from the three groups: shNC, shNC+DDP, and shTACSTD2+DDP and soft threshold set to 13 (Figure 6B, C). The gene discussed is TACSTD2; the disease is ovarian carcinoma.